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DoMo Genetics for Oncology

HOW DOES IT WORK?

Our Oncology Products

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Rapid-ISH Integra
FISH Reagent | DoMo Genetics Line

A reagent for in situ hybridizations (FISH and CISH) simply added to the molecular probe, reduces the total test time (from the slide to the diagnosis) to only 160 minutes while maintaining the quality of the test.

Using Rapid-ISH Integra also reduces the total cost of the test up to -50%.

Particularly suitable for standard tissues and samples (for example breast cancer tissues).

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Rapid-ISH Integra Plus
FISH Reagent | DoMo Genetics Line

A reagent for in situ hybridizations (Fast FISH and CISH) simply added to the molecular probe, reduces the total test time (from the slide to the diagnosis) to only 160 minutes while maintaining the quality of the test.

Using Rapid-ISH Integra Plus also reduces the total cost of the test up to -50%.

Particularly suitable for difficult tissues and samples (for example lung and brain cancer tissues).

SKU/Item number: 031114 MO

References:

Chromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast.
Cremonini A, Saragoni L, Morandi L, Corradini AG, Ravaioli C, Di Oto E, Limarzi F, Sanchez AM, Cucchi MC, Masetti R, Quinn C, Foschini MP. Virchows Arch. 2021 Aug;479(2):345-354. doi: 10.1007/s00428-021-03028-2. Epub 2021 Feb 3. PMID: 33534004; PMCID: PMC8364532. 

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

References:

Chromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast.
Cremonini A, Saragoni L, Morandi L, Corradini AG, Ravaioli C, Di Oto E, Limarzi F, Sanchez AM, Cucchi MC, Masetti R, Quinn C, Foschini MP. Virchows Arch. 2021 Aug;479(2):345-354. doi: 10.1007/s00428-021-03028-2. Epub 2021 Feb 3. PMID: 33534004; PMCID: PMC8364532. 

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

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Rapid-ISH Integra Recovery
ISH Reagents | DoMo Genetics Line

A reagent for in situ hybridizations (FISH and CISH) simply added to the molecular probe, reduces the total test time (from the slide to the diagnosis) to only 160 minutes while maintaining the quality of the test.

Using Rapid-ISH Integra Plus also reduces the total cost of the test up to -50%.

This product is recommended in the retreatment of the samples that fail to give valuable results after a first test both with a standard long method and with a Rapid-ISH based method.

SKU/Item number: 031114-DM

References:

Chromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast.
Cremonini A, Saragoni L, Morandi L, Corradini AG, Ravaioli C, Di Oto E, Limarzi F, Sanchez AM, Cucchi MC, Masetti R, Quinn C, Foschini MP. Virchows Arch. 2021 Aug;479(2):345-354. doi: 10.1007/s00428-021-03028-2. Epub 2021 Feb 3. PMID: 33534004; PMCID: PMC8364532. 

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

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Rapid-ISH Hemato
CISH Reagent | In Situ Hybridization Reagents DoMo Genetics Line

A reagent for in situ hybridizations (FISH or CISH) simply added to the molecular probe, reduces the total test time (from the slide to the diagnosis) to only 160 minutes while maintaining the quality of the test.

Using Rapid-ISH Hemato also reduces the total cost of the test up to -50%.

This product is recommended for oncohematological samples.

SKU/Item number: 031114 HE

References:

Chromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast.
Cremonini A, Saragoni L, Morandi L, Corradini AG, Ravaioli C, Di Oto E, Limarzi F, Sanchez AM, Cucchi MC, Masetti R, Quinn C, Foschini MP. Virchows Arch. 2021 Aug;479(2):345-354. doi: 10.1007/s00428-021-03028-2. Epub 2021 Feb 3. PMID: 33534004; PMCID: PMC8364532. 

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

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Smart-ISH Solve
FISH Buffer | DoMo Genetics Line FISH Buffer

A buffer for in situ hybridizations to be added to the molecular probe, to reduce the total test cost up to 50% while maintaining the quality of the test and its turnaround time.

This product is suitable for all the types of tissues and samples.

References:

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

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Easy FISH Pretreatment Kit

Are you bored by preparing and checking lab solution every single day?

Does it consume your time and resources?

In our experience, we can respond together, YES!

OACP presents EASY FISH Pre-treatment solutions KIT (for FFPE Tissues): a fully compatible product that has been studied to make FISH Tests easier.

With only one kit you can perform the pre-treatment protocol for multiple tissue types and probes.

It is all about an initial set-up and the rest of the lab work will be easy, simple and with a lower risk of making errors.

EASY FISH is compatible not only with the Rapid-ISH and Smart- ISH buffers but with almost all the commercial probes already in the market.

We work to make the lab life better and easier.

Ask for a DEMO at ask@oacp.it or by filling the contact form.

We can also customize the kit composition according to our needs.

References:

Chromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast.
Cremonini A, Saragoni L, Morandi L, Corradini AG, Ravaioli C, Di Oto E, Limarzi F, Sanchez AM, Cucchi MC, Masetti R, Quinn C, Foschini MP. Virchows Arch. 2021 Aug;479(2):345-354. doi: 10.1007/s00428-021-03028-2. Epub 2021 Feb 3. PMID: 33534004; PMCID: PMC8364532. 

HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray-Fluorescence In Situ Hydridization-Based Study.
Muscatello LV, Di Oto E, Sarli G, Monti V, Foschini MP, Benazzi C, Brunetti B. Vet Pathol.
2018 Nov 1:300985818808531. doi: 10.1177/0300985818808531.

X chromosome gain is related to increased androgen receptor expression in male breast cancer.
Di Oto E, Biserni GB, Varga Z, Morandi L, Cucchi MC, Masetti R, Foschini MP.

Virchows Arch. 2018 Aug; 473(2): 155-163. doi: 10.1007/s00428-018-2377-2. Epub 2018 May 25.

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TITAN FISH PROBES
Welcome to the new standard

With the OaCP FISH Probes, labs will acquire the new standard in the in Situ Hybridization technologies.

Rapidity, Sensitivity, Specificity, Accuracy, Reliability, Simplicity,
Low background signal for easy and better interpretation.

MORE THAN 60 PROBES LIST
MORE THAN 300 CUSTOM PROBES
HYBRIDIZATION TIMES:
40MINS – 2HOURS – O/N

References:

FFPE sample and U118 Cell Line (ROS microdeletion)

Credits: Dr.ssa A.Testi, Dr.ssa V.Monti, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano

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